peter doshi :: Article Creator New Research Reports On Financial Entanglements Between FDA Chiefs And The Drug Industry An investigation published by The BMJ today raises concerns about financial entanglements between US Food and Drug Administration (FDA) chiefs and the drug and medical device companies they are responsible for regulating. Regulations prohibit FDA employees from holding financial interests in any FDA "significantly regulated organization" and the FDA says it takes conflicts of interest seriously, but Peter Doshi, senior editor at The BMJ, finds that financial interests with the drug industry are common among its leaders. Doshi reports that nine of the FDA's past 10 commissioners went on to work for the drug industry or serve on the board of directors of a drug company. That includes Margaret Hamburg, who led FDA between 2009 and 2015, but whose story is less well known. Like her colleagues, Margaret Hamburg h
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Coxsackievirus in children: How serious is it? - Mayo Clinic News Network
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My 3-year-old grandchild has coxsackievirus. It's going around the child care center. Is this a serious illness?
Answer From Pritish K. Tosh, M.D.
Most coxsackievirus infections aren't serious.
Many people have no symptoms or only mild ones. Some common symptoms are:
Fever.
Being very tired.
Rash.
Sore throat.
Mouth sores.
Painful swallowing.
Headache.
Coxsackievirus is sometimes written as two words: Coxsackie virus. Many strains of coxsackievirus exist. But they all belong to a group of viruses called enteroviruses.
The virus spreads when you touch an object with the virus on it and then touch your face. You also can catch the virus by breathing it in when someone who has the virus coughs or sneezes near you.
Illness with this group of viruses happens most often in children less than 1 year old. But anyone can catch the virus. The virus spreads throughout the year. In places with different seasons, cases may go up in the summer and the fall.
For people who catch the virus, health care providers suggest staying home, getting rest and drinking plenty of fluids. Pain medicines that you can get without a prescription can be used for pain or fever. Medicines that are used to treat bacterial infections, called antibiotics, won't help the body clear out coxsackievirus or any other viral infection.
Very rarely, more-serious symptoms can happen. Some strains of this virus can cause:
Severe hand-foot-and-mouth disease.
Chest pain, called pleurodynia.
Inflammation of the heart muscle, called myocarditis.
The tissue around the brain to swell, a disease called meningitis.
Infection in the brain, also called encephalitis.
If you're worried about your grandchild's symptoms, call a health care provider. Some symptoms to watch for are a high fever, dehydration, or severe headache.
With
Pritish K. Tosh, M.D.
Dec. 28, 2022
Modlin JF. Enterovirus and parechovirus infections: Epidemiology and pathogenesis. https://www.uptodate.com/contents/search. Accessed Nov. 22, 2022.
Modlin JF. Enterovirus and parechovirus infections: Clinical features, laboratory diagnosis, treatment, and prevention. https://www.uptodate.com/contents/search. Accessed Nov. 22, 2022.
Loscalzo J, et al., eds. Enterovirus, parechovirus, and reovirus infections. In: Harrison's Principles of Internal Medicine. 21st ed. McGraw Hill; 2022. https://accessmedicine.mhmedical.com. Accessed Nov. 22, 2022.
Overview of enterovirus infections. Merck Manual Professional Version. https://www.merckmanuals.com/professional/infectious-diseases/enteroviruses/overview-of-enterovirus-infections. Accessed Nov. 22, 2022.
Prevention and treatment. Centers for Disease Control and Prevention. https://www.cdc.gov/non-polio-enterovirus/about/prevention-treatment.html. Accessed Nov. 22, 2022.
Enteroviruses. Centers for Disease Control and Prevention. https://www.cdc.gov/dotw/enteroviruses/index.html. Accessed Nov. 22, 2022.
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