Adult Vaccinations

The Independent State of Samoa issued an update regarding the extensive measles outbreak rapidly spreading in this Pacific Island country. In a Tweet published late on November 26, 2019, the Samoa Ministry of Health reported 2,686 measles cases since the outbreak began in October 2019. Furthermore, 249 additional measles cases were recorded in the last 24 hours.  To alert the international community, the Government of Samoa officially declared a state of emergency on November 15th.  To date, 33 measles-related fatalities have been recorded. Most of these deaths were children under 4 years of age. Samoa has attributed the 1st case of measles to someone who traveled from New Zealand to Samoa in late August, the Ministry of Foreign Affairs and Trade confirmed to Stuff.  In response to this serious situation, an extensive vaccination campaign was launched on November 20th. According to the Samoan government, this effort has successfully vaccinated 33,085 individuals ...

LONDON--(BUSINESS WIRE)--Nov 26, 2019-- Prokarium, a private biotechnology company developing vaccines against infectious diseases and immunotherapy for solid tumors, has received Clinical Trial Authorization (CTA) acceptance from the UK Medicines and Healthcare products Regulatory Agency (MHRA) to run a first-in-human Phase I trial with Entervax™, a bivalent vaccine against enteric fever. Prokarium anticipates dosing of the first subject to begin in the first quarter of 2020. The trial is part of a collaboration between Prokarium and the Wellcome Trust, which invested £4.6m earlier this year to fund two clinical trials with Entervax™. The MHRA approved trial is a randomized, double-blind, placebo-controlled study designed to evaluate the safety and immunogenicity of Entervax™ in healthy volunteers. “The Entervax™ CTA is additional validation of our vaccine candidate and underlying technology. Importantly, it brings Entervax™ one step closer to those who need it” said Prokarium’s ...

Children in southern districts of Sindh are going to get a vaccine against typhoid during a two-week immunisation campaign. Since 2017, most of Pakistan’s 10,000 cases of typhoid have been documented in southern Sindh. Ten million children between nine months and 15 years would get lifesaving vaccines. The new typhoid vaccine was approved in 2018 by the World Health Organisation and has been provided by Gavi, a Geneva-based GAVI vaccine alliance, backed by the Bill & Melinda Gates Foundation, the WHO, the World Bank, and UNICEF. The vaccine has been provided free-of-cost to the Pakistani government. By embarking upon the campaign, Pakistan has become the first country in the world to introduce a new typhoid vaccine aimed to handle an ongoing outbreak of a drug-resistant strain of the potentially lethal disease. By 2021, it will become a nationwide program and a part of routine childhood vaccination schedules. Typhoid is a bacterial infection affecting children between one and 1...

KARACHI, Pakistan — Early this year Muhammad Haider Sajjad, a thin bespectacled boy of 15, was hospitalised in Karachi, Pakistan's commercial capital. Doctors suspected typhoid, but when the most common antibiotics failed to work, the boy's family began to panic. Sajjad is one of more than 11,000 people, mostly children, to have contracted a drug-resistant strain of the infection in the country since 2016, and which experts say risks spreading internationally. He survived, but hundreds have died, predominantly in the southern province of Sindh. In response Pakistan's government, already battling outbreaks of polio and dengue, has launched a huge foreign-funded vaccination drive that began on Nov 15. Some 3.4 million children have been vaccinated in the last four days in Karachi and the neighbouring city of Hyderabad where the outbreak was first reported, said James Fulker, a spokesman for GAVI, a Geneva-based partnership funded by the Bill & Melinda Gates F...

KARACHI, Pakistan (Reuters) - Early this year Muhammad Haider Sajjad, a thin bespectacled boy of 15, was hospitalized in Karachi, Pakistan’s commercial capital. FILE PHOTO: A student reacts as she gets a free anti-typhoid vaccine during the immunisation campaign at a school in Karachi, Pakistan November 20, 2019. REUTERS/Akhtar Soomro/File Photo Doctors suspected typhoid, but when the most common antibiotics failed to work, the boy’s family began to panic. Sajjad is one of more than 11,000 people, mostly children, to have contracted a drug-resistant strain of the infection in the country since 2016, and which experts say risks spreading internationally. He survived, but hundreds have died, predominantly in the southern province of Sindh. In response Pakistan’s government, already battling outbreaks of polio and dengue, has launched a huge foreign-funded vaccination drive that began on Nov 15. Some 3.4 million children have been vaccinated in the last four days in Karachi...

Summary In science news around the world, a Swiss firm announces that, in a first, it has used the CRISPR gene editor to help two people with blood diseases—sickle cell anemia in one and beta thalassemia in the other—caused by mutations to their hemoglobin gene. Brazil's government reports that development, most of it illegal, destroyed more than 9700 square kilometers of Amazon rainforest in the year ending in July, an increase of 30% from the previous year and the highest rate of deforestation since 2007–08. Coincidentally, XPRIZE announces a purse of $10 million in a new competition to develop technology to help survey and protect biodiversity in tropical rainforests. Pakistan plans widespread use of a new typhoid vaccine to help end an outbreak of an extensively drug resistant form of Salmonella enterica Typhi, a sometimes deadly bacterium spread by contaminated water and food. The U.S. President's Council of Advisors on Science and Technology holds its first meeting un...

The holidays are just around the corner, and often they include vacations. If you have international travel plans, especially to developing nations, it’s important to talk to your doctor about vaccines to keep you safe. Routine vaccinations, based on age and health conditions, are recommended for all travelers. This is particularly important considering that many countries don’t have robust pediatric vaccination programs, so travelers will not benefit from the herd immunity afforded by such programs. Tetanus vaccination is recommended every 10 years, but international travelers should be vaccinated if it has been five or more years since the last booster dose. Tetanus is found in the environment and the toxin it releases during infection causes lockjaw. Travelers should receive the vaccine in case of an accidental injury because it may be difficult to find good medical care. The vaccine also includes protection against diphtheria, a serious throat infection, and may include prote...

[unable to retrieve full-text content] Pakistan rolls out new typhoid vaccine to fight resistant strain    SciDev.Net https://ift.tt/2KwDddl

The Government of Samoa officially declared a state of emergency 4-weeks after a measles outbreak which has claimed 15 lives. According to a UNICEF press release on November 19, 2019, Samoan health officials have confirmed 14 children and 1 adult fatality related to this measles virus outbreak. All Samoan schools have been temporarily closed and children under 17 years old have been advised by the Government not to attend public gatherings to contain the spread of this vaccine-preventable disease. Measles is a highly contagious virus, measles is a disease that spreads from person to person by breathing, coughing, or sneezing. UNICEF said in this statement it ‘has deployed health and communication staff in Samoa to boost the government’s immunization campaign and delivered a total of 110,500 doses of measles-containing vaccines (100,000 MR and 10,500 MMR) and 30,000 Vitamin A tablets.  In addition, 6 refrigerators and three emergency response trolleys used as immuniz...

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WHO, Unicef and Pakistani experts declare new typhoid vaccine ‘very safe’ As a mass vaccination drive against extensively drug-resistant (XDR) typhoid started in Karachi and other parts of Sindh on Monday, the World Health Organisation (WHO), Unicef and Pakistani child specialists and doctors said the newly-introduced vaccine was fully safe and would prevent children from nine months to 15 years of age from typhoid, which has emerged as major health issue in the province. “TCV [Typhoid Conjugate Vaccine) is very safe vaccine and no serious adverse events were observed after its administration. This vaccine is pre-qualified by the World Health Organisation, which means that its production is rigorously monitored by WHO. TCV is recommended for use by WHO because it’s safe and effective in granting the protection [against XDR typhoid],” said Dr Palitha Gunarathna Mahipala, WHO representative in Pakistan, in a message to The News on Monday. Dr Mahipala said: “Moreover, TCV was used in d...

An estimated 12 million UK citizens have a chronic medical condition, and many of them report severe mental fatigue that they characterize as “sluggishness” or “brain fog”. This condition is often as debilitating as the disease itself. A team in the University of Birmingham’s Centre for Human Brain Health investigated the link between this mental fog and inflammation – the body’s response to illness. In a study published in NeuroImage , they show that inflammation appears to have a particular negative impact on the brain’s readiness to reach and maintain an alert state. Dr Ali Mazaheri and Professor Jane Raymond of the University’s Centre for Human Brain Health, are the senior authors of the study. Mazaheri says: “Scientists have long suspected a link between inflammation and cognition, but it is very difficult to be clear about the cause and effect. For example, people living with a medical condition or being very overweight might complain of cognitive impairment, but it’s hard to ...

Pakistan is the first country in the world to introduce World Health Organisation-recommended typhoid conjugate vaccine (TCV) in its national immunisation program. In this big move, an India-made vaccine Typbar TCV, will play a significant role. About 1.2 crore doses of the vaccine have been supplied by Hyderabad-based Bharat Biotech for this initiative. According to international reports, Pakistan is launching the project in Sindh province, which is the centre of an ongoing extensively drug-resistant (XDR) typhoid outbreak that began in November 2016. Zafar Mirza, Special Assistant to Prime Minister Imran Khan on Health, said, “The government has planned a phased national introduction strategy with strong, coordinated support from global and local partners.” With funding support from the Global Alliance for Vaccine Initiative (GAVI), the vaccine introduction will begin with a two-week vaccination campaign targeting one crore children. It will be introduced nationally in 2021, he s...

An estimated 12 million UK citizens have a chronic medical condition, and many of them report severe mental fatigue that they characterize as “sluggishness” or “brain fog”. This condition is often as debilitating as the disease itself. A team in the University of Birmingham’s Centre for Human Brain Health investigated the link between this mental fog and inflammation – the body’s response to illness. In a study published in NeuroImage , they show that inflammation appears to have a particular negative impact on the brain’s readiness to reach and maintain an alert state. Dr Ali Mazaheri and Professor Jane Raymond of the University’s Centre for Human Brain Health, are the senior authors of the study. Mazaheri says: “Scientists have long suspected a link between inflammation and cognition, but it is very difficult to be clear about the cause and effect. For example, people living with a medical condition or being very overweight might complain of cognitive impairment, but it’s hard to ...

Karachi, 15 November 2019 - Pakistan today became the first country in the world to introduce the World Health Organization (WHO)-recommended typhoid conjugate vaccine (TCV) into its routine immunization programme. It is the first typhoid vaccine that can be given to children as young as 6 months of age and confers longer term protection against typhoid. The government of Pakistan is launching the vaccine introduction with a campaign in Sindh Province, which is the centre of an ongoing extensively drug-resistant (XDR) typhoid outbreak that began in November 2016. “Children are disproportionately affected by typhoid and its associated complications, and we strongly believe that TCV would protect our children against potentially fatal disease of typhoid,” said Dr Zafar Mirza, Special Assistant to the Prime Minister on Health. “Starting with Sindh Province, where the need is most urgent, the government of Pakistan has planned a phased national introduction strategy with strong, coordin...

Inflammation, including the kind resulting from mild colds, may impact the brain’s ability to become and stay alert, something often referred to as ‘brain fog.’ The findings come from a new study out of the University of Birmingham, which injected participants with a salmonella typhoid vaccine in order to temporarily induce inflammation in their bodies. Inflammation in the body isn’t unusual — this is a normal response to illnesses and can result from something as simple as catching a virus or developing an infection. However, inflammation should be a temporary state; when chronic, it causes all sorts of health issues, including potentially the development of cancer. Chronic inflammation has been linked to obesity, low-quality diets, autoimmune diseases, and more. Regardless of what is causing it, the new study found that inflammation in the body directly impacts the brain’s ability to become and then stay alert. As a consequence, someone experiencing inflammation may find that the...

Karachi: Pakistan has become the first country in the world to have launched a new vaccine to combat typhoid. Pakistan officials said on Friday that this decision has been taken after the recent increase in typhoid cases in the country. The World Health Organization has approved this vaccine. It will be used in a two-week immunization campaign in Sindh province. Sindh is the province of Pakistan where 10,000 typhoid cases have been reported since 2017. Health Minister of Sindh Province, Azra Pechhuho has told in Karachi on Friday, 'Two weeks of the campaign is starting from today. Under this, 1 crore children from 9 months to 15 years will be vaccinated. After a two-week campaign in Sindh, this vaccine can be used in other states in the next few years. Pakistan spends a very small amount on its health budget and its large population is vulnerable to diseases like typhoid. In 2017, 63% of typhoid cases were reported, of which 70 percent were children. Pakistan has been provided ...

Scientists at the University of Birmingham in collaboration with the University of Amsterdam have uncovered a possible explanation for the mental sluggishness that often accompanies illness. An estimated 12M UK citizens have a chronic medical condition, and many of them report severe mental fatigue that they characterize as 'sluggishness' or 'brain fog'. This condition is often as debilitating as the disease itself. A team in the University's Centre for Human Brain Health investigated the link between this mental fog and inflammation -- the body's response to illness. In a study published in Neuroimage , they show that inflammation appears to have a particular negative impact on the brain's readiness to reach and maintain an alert state. Dr Ali Mazaheri and Professor Jane Raymond of the University's Centre for Human Brain Health, are the senior authors of the study. Dr Mazaheri says: "Scientists have long suspected a link between inflammation an...

Scientists at the University of Birmingham in collaboration with the University of Amsterdam have uncovered a possible explanation for the mental sluggishness that often accompanies illness. An estimated 12M UK citizens have a chronic medical condition, and many of them report severe mental fatigue that they characterize as 'sluggishness' or 'brain fog'. This condition is often as debilitating as the disease itself. A team in the University's Centre for Human Brain Health investigated the link between this mental fog and inflammation - the body's response to illness. In a study published in Neuroimage , they show that inflammation appears to have a particular negative impact on the brain's readiness to reach and maintain an alert state. Dr Ali Mazaheri and Professor Jane Raymond of the University's Centre for Human Brain Health, are the senior authors of the study. Dr Mazaheri says: "Scientists have long suspected a link between inflammation an...

Pakistan on Friday became the first country in the world to introduce a new typhoid vaccine in an effort to combat a drug-resistant strain of the potentially fatal disease in the Sindh province, officials said. Pakistani health officials have reported an ongoing outbreak of an extensively drug-resistant typhoid fever that began in the country in November 2016. The strain of Salmonella Typhi bacteria, which has become a so-called “superbug”, has so far infected around 11,000 people in the country, with Sindh province the worst-hit. According to experts, death rates among those infected by the “superbug” could rise dramatically to as much as 20%. The typhoid conjugate vaccine (TCV) was introduced at a function in Karachi where Zafar Mirza, special assistant to the prime minister on health, and Azra Fazal Pechuho, provincial minister of health, were present. Pakistan has become the first country in the world to introduce TCV into its routine immunisation programme through a campaign m...