The Top Doctors in Westchester County Offer Expert Care in 2023

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preventive medicine doctors near me :: Article Creator What Is A Primary Care Physician? Staying healthy is more than just going to the doctor when you're sick. It's about having a health care team that not only addresses your concerns and illnesses but also takes a proactive approach to help you stay healthy. A primary care physician plays an important part in helping you stay healthy. They're also sometimes called primary care providers, or PCPs. They're often the first contact you or your family members have with the health care system. They offer care for preventing, treating, and curing common illnesses as well as promoting better health. Research shows that having access to primary care can improve your health and wellness. Your primary care physician is designed to be your first point of contact when you have a health concern. They can handle many common issues and refer you to a specialist if you need one. (Photo ...
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CDC Panel Votes to Recommend Shingrix for Immunocompromised Adults - Monthly Prescribing Reference

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The Centers for Disease Control and Prevention's (CDC) Advisory Committee on Immunization Practices (ACIP) voted unanimously to recommend Shingrix (zoster vaccine recombinant, adjuvanted) for the prevention of herpes zoster (shingles) and its complications in adults 19 years of age and older who are, or will be immunodeficient or immunosuppressed due to disease or therapy.

Shingrix is intended for intramuscular injection in 2 doses separated by 2 to 6 months in immunocompetent adults. In adults who are or will be immunodeficient or immunosuppressed due to known disease or therapy and who would benefit from a shorter vaccination schedule, the second dose may be administered 1 to 2 months after the first dose.

The recommendation was based on data from clinical studies that assessed the efficacy and safety of Shingrix in adults 18 years of age and older who previously had an autologous hematopoietic stem cell transplant (auHSCT; N=1721) and in those undergoing treatment for hematologic malignancies (N=515; post-hoc analysis).

Shingrix was found to be 68.2% (95% CI, 55.5-77.6) effective against the development of herpes zoster in immunocompromised adults who received an auHSCT 50 to 70 days prior to the first dose and who were expected to receive prophylactic antiviral therapy for at most 6 months post-transplant. In the hematologic malignancy study, post hoc analysis showed Shingrix was 87.2% (95% CI, 44.2-98.6) effective against herpes zoster development.

The approval was further supported by safety and immunogenicity data in adults who were, or were anticipated to be immunodeficient or immunosuppressed due to known disease or therapy, including patients with HIV, solid tumors, and renal transplants.

The recommendations will be reviewed for approval by the director of the CDC and the US Department of Health and Human Services. Following approval, the final recommendations will be published in a future Morbidity and Mortality Weekly Report (MMWR).

"Today's recommendation is an important clinical advancement in providing protection from shingles and its complications to adults with immunodeficiency or immunosuppression," said Sabine Luik, Chief Medical Officer & SVP Global Medical Regulatory & Quality, GSK. "The ACIP's vote helps to address an existing unmet need as individuals who are immunocompromised are at an increased risk of the disease."

Shingrix is currently approved for the prevention of herpes zoster in adults 50 years of age and older. It is also approved for the prevention of herpes zoster in adults 18 years of age and older who are or who will be at increased risk of herpes zoster due to immunodeficiency or immunosuppression caused by known disease or therapy.

Reference

US Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices votes unanimously to recommend Shingrix for immunocompromised adults aged 19 and up. News release. GlaxoSmithKline. October 20, 2021. Accessed October 21, 2021. https://www.gsk.com/en-gb/media/press-releases/votes-unanimously-to-recommend-shingrix-for-immunocompromised-adults-aged-19-and-up/. 

Topics:

Herpes Zoster Virus Immunization Infectious Disease Vaccines Viral Infections

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