How Many Physicians Have Opted Out of the Medicare Program?

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peter doshi :: Article Creator New Research Reports On Financial Entanglements Between FDA Chiefs And The Drug Industry An investigation published by The BMJ today raises concerns about financial entanglements between US Food and Drug Administration (FDA) chiefs and the drug and medical device companies they are responsible for regulating. Regulations prohibit FDA employees from holding financial interests in any FDA "significantly regulated organization" and the FDA says it takes conflicts of interest seriously, but Peter Doshi, senior editor at The BMJ, finds that financial interests with the drug industry are common among its leaders. Doshi reports that nine of the FDA's past 10 commissioners went on to work for the drug industry or serve on the board of directors of a drug company. That includes Margaret Hamburg, who led FDA between 2009 and 2015, but whose story is less well known. Like her colleagues, Margaret Hamburg h

Dental Procedures - Epilepsy Foundation

Before a dental procedure, levels of antiepileptic drugs (AEDs) should be measured and adjusted based on the individual patient's history. The dental team should be informed about the patient's seizure type and first aid.

Seizure-precipitating factors, such as sleep deprivation or alcohol intake, should be avoided before the procedure.

Methohexital was compared to local anesthetic in conservative dental procedures. Although a seizure occurred in only 1 out of 200 patients, the main disadvantage of its use over local anesthetic is side effects, including tongue movements, coughing, hiccoughs, and prolonged lethargy after the procedure.105

Seizures that occur during or after a dental procedure can occur with N2O104 and methohexital.51 In these studies, seizures most often occurred in patients with undiagnosed epilepsy or those who missed a dose of their antiepileptic medications on the day of the dental procedure.

Other studies demonstrate that N2O and propofol in subanesthetic doses for conscious sedation are safe for mentally handicapped epilepsy patients who undergo dental procedures.45 N2O and propofol are almost always safe in epilepsy patients who are adequately treated with AEDs.

Adapted from: Najjar S, Devinsky O, Rosenberg AD, et al. Procedures in epilepsy patients. In: Ettinger AB and Devinsky O, eds. Managing epilepsy and co-existing disorders. Boston: Butterworth-Heinemann; 2002;499–513. With permission from Elsevier (www.elsevier.com).

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