The Top Doctors in Westchester County Offer Expert Care in 2023

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mesa primary care :: Article Creator Kaiser Permanente Is Building A $25 Million Primary-care Facility In ... Kaiser Permanente is spending $25 million to build the first two phases of a medical office complex at the corner of Harbor and MacArthur boulevards in Costa Mesa. The building is set to span 48,000 square feet and mark Kaiser's 15th primary care site in Orange County. The health plan, a unit of Oakland-based Kaiser Foundation Health Plan, is OC's largest with more than 300,000 local members. The first patients at the Costa Mesa facility are expected in September or October. Demographics are the key driver for the new complex, said Judy White, a Kaiser medical group administrator. "We're growing very rapidly," said Kaiser Spokeswoman Judy White. "This will serve our members in Costa Mesa, Santa Ana, Huntington Beach and Westminster." Kaiser uses input from employers and housing developers, among other ...
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Experimental TB vaccine a ‘game changer’ that offers new hope - Business Day

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The Bacille Calmette Guérin (BCG) vaccine, routinely given to babies around the world, was developed more than 90 years ago, and provides limited protection that wanes by adolescence. GSK’s candidate vaccine M72/AS01E was tested in 3,300 HIV negative adults in Kenya, SA and Zambia who had latent TB, and the results of the phase 2b trial were published in the New England Journal of Medicine this week.  

Participants were either given two doses of the vaccine or a placebo, and followed for three years to see if they developed pulmonary TB. Only 13 people who received the shots got TB, compared to 26 who did not.

“The trial is a game changer because it is the first time a TB vaccine candidate has been shown to offer protection to people who are already infected with the Mycobacterium tuberculosis bacillus. Those people, about two thirds of SA adults, are at risk of progression to TB disease,” said the study’s principal investigator Mark Hatherill, director of the SA Tuberculosis Vaccine Initiative.

GSK’s experimental vaccine contains TB proteins that trigger an immune response, but the mechanism is not yet fully understood, said Hatherill.

Further research was needed to determine whether the vaccine protected people who had not yet been infected with TB and those living with HIV, and to determine whether the protection was durable. Ideally a vaccine should confer protection for at least 10 years, he said.

“These questions must be asked and answered in a bigger confirmatory trial or trials, which will need a funding commitment from government and non-governmental stakeholders worldwide. These answers will be critical in getting the vaccine to a broad market,” he said.

In a separate development, French pharmaceutical manufacturer Sanofi announced on Thursday that it had slashed the price of its TB antibiotic rifapentine by two thirds, to a net ex-factory price of $15 for eligible countries in low and middle-income countries, including SA.



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