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mesa primary care :: Article Creator Kaiser Permanente Is Building A $25 Million Primary-care Facility In ... Kaiser Permanente is spending $25 million to build the first two phases of a medical office complex at the corner of Harbor and MacArthur boulevards in Costa Mesa. The building is set to span 48,000 square feet and mark Kaiser's 15th primary care site in Orange County. The health plan, a unit of Oakland-based Kaiser Foundation Health Plan, is OC's largest with more than 300,000 local members. The first patients at the Costa Mesa facility are expected in September or October. Demographics are the key driver for the new complex, said Judy White, a Kaiser medical group administrator. "We're growing very rapidly," said Kaiser Spokeswoman Judy White. "This will serve our members in Costa Mesa, Santa Ana, Huntington Beach and Westminster." Kaiser uses input from employers and housing developers, among other ...

Vaccination and Risk of Childhood IgA Vasculitis

Abstract

BACKGROUND AND OBJECTIVES: Immunoglobulin A vasculitis (IgAV) might develop after vaccination. However, this potential relationship is essentially based on case reports, and robust pharmaco-epidemiologic data are scarce. We aimed to investigate the effect of vaccination on short-term risk of IgAV in children.

METHODS: We enrolled children <18 years old with IgAV seen in 5 pediatric departments from 2011 to 2016. Data on vaccinations administered during the year preceding IgAV onset were collected from immunization records. With a case-crossover method and by using conditional logistic-regression analyses, odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by comparing vaccine exposure during the 3-month “index period” immediately preceding IgAV onset to that during 3 consecutive 3-month “control” periods immediately before the index period. Stratifications by season, year of onset, infection history, age, sex, type, or number of vaccines were performed. Sensitivity analyses used 1-, 1.5-, or 2-month index and control periods.

RESULTS: Among 167 children (mean age: 6.7 years) enrolled, 42 (25%) received ≥1 vaccine during the year before IgAV onset. Fifteen (9%) children were vaccinated during the 3-month index period as compared with 4% to 7% during the 3 control periods. The OR for IgAV occurring within the 3 months after vaccination was 1.6 (95% CI: 0.8–3.0). Analyses of IgAV risk within 1, 1.5, or 2 months of vaccination yielded ORs of 1.4 (95% CI: 0.5–3.5), 1.4 (95% CI: 0.6–3.2), and 1.3 (95% CI: 0.6–2.6), respectively. Stratifications revealed no significant association.

CONCLUSIONS: Vaccination may not be a major etiological factor of childhood IgAV.



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