gastroenterology internal medicine :: Article CreatorDivision Of Gastroenterology And Hepatology
Who We Are
The Saint Louis University Division of Gastroenterology and Hepatology has a long history of excellence in clinical care, education, and research. We plan to build on that history as we expand our reach. Our vision is rooted in leadership, education, and care.
Our faculty are renowned for their expertise, and we want to channel our talents into recognition as leaders in the field, regionally, nationally, and internationally. This will open opportunities for our trainees to explore their talents in education and research. These goals can only be accomplished by continuing our delivery of state-of-the-art care with compassion.
Letter from the Division Director
Thank you for your interest and visiting our website. Our mission is to provide the best compassionate care to our patients, an excellent education for our trainees and community physicians, and to continue to advance knowledge in field of gastroenterology and hepatology through state-of-the-art research. Our vision is rooted in leadership, education, and care with the following goals:
Leading the way to new discoveries through research, clinical trials, and quality improvement Training the next generation providers through comprehensive educational experiences, outreach events, and focusing on all levels of learners (medical students to post-doctoral fellows) Cultivating a clinical practice rooted in collaboration, quality, and efficiency With faculty members recognized as experts in their fields, nationally and internationally, they serve in a variety of capacities from Missouri Governor for the American College of Gastroenterology (ACG), American Board of Internal Medicine exam writing, American Society for Gastrointestinal Endoscopy training committee, as well as local service to the university and hospital. By channeling our skills and service, we will open opportunities for our trainees to explore their talents in education and research.
These goals can only be accomplished by continuing our delivery of state-of-the-art care with compassion. From clinic to endoscopy, transplant to motility, our faculty, advanced practice providers, trainees, nurses, and staff care about our patients. Whether concerns are new or old, mild to severe, atypical to routine we can help. Our advanced endoscopists, gastroenterologists, and hepatologists are constantly researching and expanding their knowledge to nurture the future of our field as well as the patients we so deeply cherish.
Please feel free to explore our division and learn more about our faculty, students, and research programs. We are always looking for motivated and talented staff, trainees, and providers to join as members of the Division, or to collaborate with us and support causes close to our hearts.
Our Mission
We provide the best compassionate care to our patients, excellent education for our trainees and community physicians, and continue to advance knowledge in the field of gastroenterology and hepatology through state-of-the-art research.
Wing-Kin Syn, M.D., Ph.D.
Division director of Gastroenterology and Hepatology
Gastroenterology And Hepatology Fellowship
Gastroenterology and Hepatology Training
During the program, fellows receive training in the cognitive aspects of consultative gastroenterology and hepatology, in gastrointestinal endoscopy and liver biopsies, and have research opportunities. Fellows also have an opportunity to spend six months in laboratory-based or clinical research. An amalgamation of these clinical, procedural and research experiences provides the foundation for a career in academic medicine and scholarly clinical practice.
The role of the gastrointestinal specialist has been modified with the changes in health care delivery and the advent of managed care. We are cognizant of these changes and have designed our program to be sufficiently flexible to meet our trainees' needs and allow for future success.
This includes creating the dual-pathway training option where a trainee will be board-eligible in both gastroenterology and transplant hepatology in only three years.
Complex problems in gastroenterology often require a team approach. We have excellent collaborative relations with GI and liver transplant surgeons, diagnostic and therapeutic radiologists, and GI pathologists who regularly interact with us in our patients' care and research efforts. As a result of this team approach, we are proud to offer the newly ACGME-approved dual-pathway training in our fellowship. This is an exciting opportunity for those interested in being board-eligible in gastroenterology and transplant hepatology. This combined program is designed to be completed in three years rather than as separate programs spanning four years. Saint Louis University has an active abdominal transplantation program.
A Supportive Environment
Our teaching hospitals provide fellows with experience treating both common medical conditions seen in community settings and complex cases treated at a major academic tertiary care referral center. Our teaching faculty is an enthusiastic and skilled group of educators, including many who are listed on St. Louis's Best Doctors List. Our faculty and staff are known to be approachable, friendly, and supportive.
Fellows are regularly instructed at the bedside by dedicated clinical educators who provide a truly diverse and varied experience. Fellows develop excellent clinical and patient management skills that allow them to become outstanding physicians in any environment. The program fosters self-governance and ownership of the educational experience by the fellows, encouraging self-directed, lifelong learning.
Fellowship Clinical Services
During the first year of training, fellows rotate on the gastroenterology service at SSM Health Saint Louis University Hospital and John J. Cochran Veterans Hospital. Fellows become proficient in basic endoscopic procedures. Here is a yearly breakdown:
First Year
GI Service at SSM Health Saint Louis University Hospital and John J. Cochran Veterans Hospital Proficient in basic endoscopic procedures including: Upper endoscopy Colonoscopy Endoscopic biopsy Polypectomy Esophageal dilation Endoscopic hemostasis Percutaneous endoscopic gastrostomy Second and Third Year
Liver service Pancreatiocobiliary service SLU clinics Endoscopy John J. Cochran Veterans Hospital If a trainee is interested in completing the dual-pathway for gastroenterology and transplant hepatology, they may apply in their first year to begin on the adjusted pathway during their second year. These trainees will have the same robust gastroenterology experiences with the following transplant hepatology-specific experiences:
Outpatient rotations with transplant surgery, pediatrics Pathology Participation in liver biopsies Participation in liver procurement Elective Options
Gastrointestinal radiology Pathology Pediatric and adolescent gastroenterology Advance endoscopy Hepatology Liver transplantation Colorectal surgery Academic leadership/teaching/QI project Fellowship Research
Each fellow is expected to complete a research project of clinical or basic science interest. The goal of the research component of the fellowship is to train physicians and basic scientists who want to pursue a career in academic medicine. The program develops independence under the direction of a mentor.
A major emphasis of the experience is teaching the skills necessary to perform research and win peer-reviewed funding in our current competitive climate. The research process includes experience in literature review, study design, budgeting, peer review, IRB approval, data collection, statistical analysis, and submission of an abstract for society presentation and publication in a peer-reviewed journal. In addition to the support of the teaching faculty, the fellowship program provides research support consisting of clinical research assistants, computer programming for data analysis, and graphics and audio/visual support for presentations.
Each fellow must also present their research at our annual year-end research conferences. Fellows are also encouraged to present the results of their research experiences at an annual national meeting, such as those sponsored by the American Gastroenterological Association, the American Association for the Study of Liver Diseases or the American College of Gastroenterology.
Current research activities include:
Investigation into the mechanisms of hepatic fibrogenesis Mechanism of lipotoxic liver injury (NASH) Gene regulation of hepatic collagen synthesis Regulation of hepatic stellate cell activation Effects of Kupffer cell products on hepatic stellate cells Role of oxidative stress in hepatic injury Mechanisms of inflammation and fibrosis in the pancreas Intracellular signaling in stellate cell Correlation of hepatic steatosis among cohabitants - NASH and pharmacology Effect of food-reintroduction timing post-scope Endoscopy for abnormal imaging Training Goals
The goal of training in the second and third years is for fellows to develop specific skills in keeping with their career goals. Someone interested in general gastroenterology practice might be involved in all clinical areas. Someone interested in a research-oriented academic career would place an emphasis on research. And subspecialty residents interested in a career in academic clinical hepatology might do extensive work in the liver clinic, with the liver transplant service, and with several clinical research projects. The flexibility of the curriculum in the second and third years allows our fellows to tailor their training according to their career choices.
Transplant Hepatology
Our ACGME-accredited transplant hepatology fellowship is designed for trainees who have already completed their gastroenterology training. Building on the prior training allows this one-year fellowship to deepen the trainee's knowledge while challenging them with additional skills and procedures. Our program aims to create well-rounded gastroenterologists capable of meeting 21st-century needs in a collaborative approach with their patients, other services and the medical system.
If you have any questions, please reach out and let us know.
Clinical Research Fellowship
Thank you for your interest in the unique clinical research fellowship offered by the Division of Gastroenterology and Hepatology at Saint Louis University. As a clinical research fellow (CRF), you will be an integral part of a dynamic team, reporting directly to the division director, Wing-Kin Syn, M.D.
Over the course of one year, you will be immersed in a unique blend of research and clinical training, with a specific focus on hepatology and mainly the areas of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), autoimmune liver disease and liver fibrosis. During this period, you will dedicate 50% of your time to cutting-edge research in hepatology. The division offers a rich array of ongoing research projects, giving you the opportunity to join groundbreaking initiatives. Moreover, the CRF will be strongly encouraged to design and lead their own research projects under the expert guidance of Syn or another attending physician.
The CRF will also have the distinct opportunity of being assigned co-investigator in clinical trials. This invaluable experience will empower you to develop strong clinical research skills and gain exposure to the leadership required to conduct strong and demanding prospective clinical studies.
To foster your professional growth and visibility, you will be expected to either present your studies' findings at national and/or regional gastroenterology and hepatology society meetings, or publish your work in indexed journals. Additionally, you will be an active participant in all division conferences and teaching sessions, engaging with gastroenterology fellows and expanding your knowledge within a supportive community.
The other half of the academic year will be dedicated to clinical practice. You will have the privilege of participating in the general gastroenterology clinic, where you will see and evaluate up to eight patients per half-day, under the guidance of attending physicians. Moreover, you will have the opportunity to be part of the autoimmune liver disease and MASLD (metabolic) clinics for two half-days each week, delving deeper into specialized areas.
To augment CRF clinical experience, the fellow will have the chance to complete rotations in the inpatient services of general gastroenterology and hepatology, and get experience with invasive procedures such as endoscopic procedures, liver biopsies, and paracentesis.
The CRF will also play a vital role in the division's metabolic clinic program, assuming chief responsibilities and managing the schedule of rotating residents. Your dedication to teaching and providing guidance to students and young residents will further elevate your impact as a clinician and mentor.
This position is ideal for aspiring GI/hepatology physician-researchers or physician-scientists looking to forge a successful career in the field. The CRF program is meticulously designed to harmoniously integrate research and clinical practice, ultimately enhancing patient care and pushing the boundaries of medical knowledge.
For more information, please contact:
Advanced Endoscopy Fellowship
This one-year program is designed to provide a comprehensive training experience in the evaluation and management of pancreaticobiliary conditions, among other GI disorders pertinent to the practice of advanced endoscopy.
At our high-volume tertiary center, the advanced endoscopy fellow will receive extensive training, utilizing cutting-edge equipment in our newly built endoscopy unit. This includes a wide range of advanced endoscopic techniques such as simple and complex ERCP, diagnostic and therapeutic EUS, endoscopic resection, enteral stenting, endoscopic closure therapy, and more.
The program aims to develop highly skilled endoscopists through hands-on training under the mentorship of our experienced faculty. Fellows will also have the opportunity to participate in multidisciplinary conferences and engage in clinical research.
Program Highlights:
Procedural competence: Beyond advancing technical endoscopic skills, our program emphasizes gaining cognitive (knowledge and recognition) and integrative (expertise and behavior) competencies. Extensive experience: The high volume of cases at our referral center will ensure that trainees gain procedural competence and proficiency. The flexible nature of the program allows fellows to achieve procedural competence and proficiency in EUS and ERCP, while gaining insight into other advanced endoscopic procedures such as third space endoscopy and bariatric endoscopy. Multidisciplinary approach: To provide high-quality patient care, the advanced endoscopy fellow will actively interact and coordinate management with various specialists, including surgical and medical oncologists, transplant surgeons, expert GI pathologists, radiologists, interventional radiologists, and others. Our goal is to equip fellows with the skills and knowledge to excel in the field of advanced endoscopy, preparing them to meet the evolving needs in advanced endoscopy. For more information, please contact:
Application Process
You may apply for one of our four GI fellowship positions through the Electronic Residency Application Service (ERAS). We accept applications July 1-31 for each interview season. We review applications in early August and invite applicants to interview from late August to October. Our positions will be filled through the National Residency Match Program (NRMP). We sponsor both H-1B1 and J-1 visas. All application requirements are listed with ERAS.
Research
The Division of Gastroenterology and Hepatology at Saint Louis University fosters research from the lab to patient treatment. As a leading research center, we are continually engaged in multicenter clinical trials, allowing us to offer our patients access to the latest advances in clinical care. Our physicians specialize in diagnosing and treating liver diseases that range from the evaluation of fatty liver to hepatitis B to the management of severe, complicated, end-stage liver disease awaiting transplantation.
To learn about our clinical trials, please call the Gastroenterology and Hepatology Clinical Studies Unit at 314-977-9400 to speak with a research coordinator.
View Current Clinical Trials
I joined Saint Louis University in July 2018, and have been actively involved in training as a faculty of the gastroenterology fellowship program. I served as an associate program director for the fellowship training from July 2021 to June 2023. I am greatly familiar with the rigors and rewards of training here at Saint Louis University. Our program's goal is to create well-rounded gastroenterologists capable of meeting 21st-century needs in a collaborative approach with their patients, other services and the medical system. Fellows focus on clinical outpatient experiences, inpatient services, research and special populations. The fellowship program is positioned to grow with trainees and their interests, with our talented faculty and staff facilitating their instruction. Our union with SSM Health System has provided us with more resources and rigor to further enhance the mission of training and providing care to the community. Please check out some of the information about our dual-pathway fellowships.
If you have any questions, please don't hesitate to reach out.
Kamran Qureshi, M.D.Associate professorProgram directorkamran.Qureshi@health.Slu.Edu
Alex Befeler, M.D. HepatologistProfessorMedical director of liver transplantationProgram director, transplant hepatologyalex.Befeler@health.Slu.Edu
Wing-Kin Syn, M.D. James F. King Chair in GastroenterologyProgram director, research track fellowshipwingkin.Syn@health.Slu.Edu
Wissam Kiwan, M.D.Advanced endoscopistAssistant professor of internal medicine and gastroenterologyProgram director, advanced endoscopy fellowship wissam.Kiwan@slucare.Ssmhealth.Com
Gastroenterology And Hepatology Section News
Content
March 4: The Texas Medical Center Digestive Diseases Center (DDC) held its 14th Annual Frontiers in Digestive Disease Symposium: Metabolic Communication in Digestive Diseases on March 4, 2023, at the Baylor St. Luke's Medical Center. This year's event included presentations from renowned speakers including Eugene B. Chang, M.D., from the University of Chicago, Theresa Alenghat, VMD, Ph.D., from Cincinnati Children's Hospital, and Rohit Loomba, M.D., MHSc, from the University of California San Diego, among others. It also offered breakout sessions and a poster competition which included more than 40 posters and 50 abstracts. The 2023 Poster Competition winners included:
First Place: Maple Adkins-Threats, Baylor College of Medicine – " Estrogen-related receptor gamma (ERRγ) as a transcriptional regulator of parietal cell lineage maintenance"
Second Place: Sara Di Rienzi, Baylor College of Medicine " Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling"
Third Place: Janel Peterson Baylor College of Medicine - " The role of MBNL in smooth muscle function & DM1 GI pathologies"
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