Local application MMR vaccine on lesion after surgery | European Archives of Oto-Rhino-Laryngology - MD Linx

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A sum of 31 children were assessed to quantify the efficiency of MMR vaccine in the treatment of juvenile-onset recurrent respiratory papillomatosis. Investigators treated 15 individuals in the intervention group with local application MMR vaccine on the lesion after surgery whereas 16 subjects in the control group were managed with surgical excision alone. They noticed (9.56 ± 11.03) × 108 copies/ml viral load of the intervention group and (22.01 ± 17.78) × 108 copies/ml in the control group with a significant difference between the 2 groups after treatment with the MMR vaccine. They reported a significant reduction in HPV viral load with local application MMR vaccine as adjuvant therapy.

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